Gout is a common metabolic disease characterized by high blood levels of uric acid (UA). It has emerged as a result of either the inability to excrete (get rid of) UA or overproducing it. In any case, what happens is that over time, deposits of monosodium urate in the form of the joints and other parts of the body, especially the kidneys, which is the main organ responsible for waste UA.
At some critical point of time, if the UA is developed enough, gout arthritis attack (GA) is occur.GA usually affects the joints or joints in the feet, legs special attacks, ankle, or knee. Attacks tend to occur early, often waking the patient from sleep. Built on the intensity of pain and accompanied by swelling, redness, and warmth. The difficulty is so severe that the patient may complain that even the “heavy bed sheet” to the affected area which causes unbearable pain treatment GA is generally divided into a treatment for acute attacks and chronic Treatment disease.
This article will focus on the treatment of a chronic attack. There few available choices and decisions about which path to pursue depends on a number of factors including, the duration of the attack, the location of the attack, the possibility of other processes that occur (ie, infection), and the presence of co-morbid disease patients with other conditions that could potentially be affected by increasing intervention. In treatment of the drug is covered, the rest of the ice can be beneficial because it reduces inflammation. Non ice-steroidal anti-inflammatory drugs (NSAIDs) are the most commonly used treatment for Chronic attacks.
NSAIDS should be started as soon as possible and tapered when the controlled. Unfortunately attacks, drugs have many potential side effects including stomach ulcers, kidney damage, deterioration of Hypertension, and higher risk of heart attack and stroke. They should be avoided in patients taking blood thinners. Its use in the elderly should be carefully monitored and avoided if possible. Colchicine is a time-honored remedy that prevents gout inflammation effectively. Low dose, 0.6 mg 2-3 times a day for 1-2 days can be enough to break the strike. Colchicine has a number of side effects that limit their use. These include stomach cramps, nausea, vomiting, bone marrow suppression, and neurological and muscle damage. It should not be used in patients with liver or kidney disease.
Glucocorticoids (“cortisone”) can be administered directly into the joint just in one or two affected joint or given by mouth or intramuscular. Glucocorticoids are a great alternative when NSAIDs and colchicine can not interleukin -1 used. Blocking using biological therapy is a new concept in the treatment of acute attacks gout. It is very effective but carries the disadvantage of being very expensive.